Familial Mediterranean fever as a predictor of preeclampsia in pregnancy: Case report
1 Erebouni medical center, Yerevan, Armenia.
2 Research center of Maternal and Child Health protection, Armenia.
3 Yeolyan Hematology and oncology center, Armenia.
Case Study
World Journal of Advanced Research and Reviews, 2023, 20(02), 1017–1021
Publication history:
Received on 28 August 2023; revised on 18 November 2023; accepted on 21 November 2023
Abstract:
Familial Mediterranean Fever (FMF) is an autosomal recessive auto inflammatory disorder characterized by recurrent fever and inflammation affecting the serosal membranes. Clinically, patients may experience attacks of recurrent fever and serositis, which can manifest with single or multiple simultaneous symptoms. While most patients are clinically diagnosed above the age of 2, cases diagnosed before 2 years of age, with an isolated fever clinical course, are believed to have a more severe course and an increased risk of developing amyloidosis.
Preeclampsia, a serious complication of pregnancy, is characterized by hypertension and organ damage, most commonly affecting the kidneys and liver. In this article, we present a case of a pregnant woman who was admitted during the 27rd week of pregnancy with rapidly developing preeclampsia and HELLP syndrome, despite having no previous history of complications. During the follow-up, we discovered the presence of FMF and certain thrombophilia gene mutations.
This case underscores the importance of considering specific diseases or syndromes under any presentation of preeclampsia. Timely identification of underlying conditions, such as FMF and thrombophilia, can aid in early intervention and appropriate management, potentially improving maternal and fetal outcomes
Keywords:
Familial Mediterranean Fever; Preeclampsia; Maternal and perinatal morbidity
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0