Extracts of Aloe vera and Allium sativum: potent inhibitors of pathogenic fungi
1 Department of Biology, Federal University of Technology Owerri, Nigeria.
2 Department of Biochemistry, Federal University Technology Owerri, Nigeria.
3 Department of Biochemistry, Madonna University Nigeria.
4 Department of Pharmacy, Madonna University Nigeria.
Research Article
World Journal of Advanced Research and Reviews, 2019, 01(02), 001–006.
Publication history:
Received on 16 January 2019; revised on 25 February 2019; accepted on 02 March 2019
Abstract:
Agar diffusion method was employed, in the evaluation of the potential antifungal activity of methanol extracts of Aloe vera and Allium sativum, against pathogenic Aspergillus niger and Candida albicans. Phytochemical evaluations showed the presence of tannins, saponins, flavonoids, and terpenoid in Aloe vera, while saponins, alkaloids, and flavonoids were found in Allium sativum. Plant extract concentration used in this study ranged from 5 to 100 mg/ml. A. vera showed the greatest antifungal effect against C. albicans and A. niger at 100 mg/ml with a zone of inhibition of 23 mm and 26 mm respectively. A. sativum exhibited a greater antifungal potential at extract concentration of 100 mg/ml with 42 mm and 37 mm zone of inhibition against A. niger and C. albicans. The phytochemical contents of these plants were implicated for the antifungal potentials.
Keywords:
Antifungal activity; Pathogenic fungi; Aloe vera; Allium sativum; Zone of inhibition
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