Evolution of patients with bipolar disorder according to pharmacological treatment Pediatric Hospital "Juan Manuel Márquez" 2009-2011

Mabel Aguilar Pérez 1, *, Gladys Castillo Izquierdo 2, Zenaida María Sáez 2, Juan Aguilar Valdés 3, Alina Leyva Castell 4 and Mairim Escalona Gutiérrez 4

1 Psychiatric Department, Paediatric Hospital "Juan Manuel Márquez", Havana Medical Sciences University, Cuba.
2 Psychiatric Department, Paediatric Hospital "Juan Manuel Márquez", Havana Medical Sciences University, Cuba.
3 Psychiatric Department, INHEM, Havana Medical Sciences University, Cuba, La Habana, Cuba.
4 Psychiatric Department. Paediatric Hospital "Juan Manuel Márquez", Havana Medical Sciences University, Cuba. 
 
Research Article
World Journal of Advanced Research and Reviews, 2023, 17(02), 144–154
Article DOI: 10.30574/wjarr.2023.17.2.0151
 
Publication history: 
Received on 14 December 2022; revised on 30 January 2023; accepted on 02 February 2023
 
Abstract: 
To know the evolution, according to the pharmacological treatment received, of the patients admitted to the Psychiatric Ward of the "Juan Manuel Márquez" Paediatric Hospital, with Bipolar Disorder (TB) in the period from January 2009 to December 2011, the present study. The objective is to identify the evolution of the patients three, six and twelve months after hospital discharge according to the pharmacological treatment used. A retrospective longitudinal descriptive study was carried out between May 2012 and May 2013. 81 hospitalized patients with TB were studied. The source of information was their medical records and a semi-structured interview. The data was processed in SPSS version 15 and the results are presented in statistical tables. Three months after hospital discharge, the highest percentage of patients with satisfactory clinical status had treatment with Haloperidol alone, in second place Risperdal and Carbamazepine and in third place the combination of Haloperidol and Magnesium Valproate (Mg), while Six months was Haloperidol alone, followed by the combination of Olanzapine and Lithium Carbonate, Risperdal and Mg Valproate, one year after hospital discharge the combination of Olanzapine and Lithium Carbonate was found first, followed by Risperdal with Carbamazepine and of quetiapine alone. The treatments most associated with satisfactory clinical status were: Haloperidol alone, Quetiapine alone, as well as the combinations of Risperdal and Carbamazepine, Risperdal and Mg Valproate, Olanzapine and Lithium Carbonate, and Haloperidol with Mg Valproate.
 
Keywords: 
Bipolar Disorder; Treatment; Evolution; Psychiatric
 
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