Essential thrombocythemia masked by vitamin B 12 deficiency megaloblastic anemia: A case report

Yasmina Benhalima 1, *, Benmoussa Amine 2, Fatima Ezzahra Lahlimi 1 and Illias Tazi 1

1 Department of Hematology, Mohammed VI hospital, Marrakech, Morocco.
2 Department of Hematology and oncology pediatric, CHU 20 Août, Casablanca, Morocco.
 
Case Study
World Journal of Advanced Research and Reviews, 2023, 18(03), 455–457
Article DOI: 10.30574/wjarr.2023.18.3.1095
 
Publication history: 
Received on 30 April 2023; revised on 07 June 2023; accepted on 10 June 2023
 
Abstract: 
The association of megaloblastic vitamin B12 deficiency anemia and essential thrombocythemia is very rarely described in the literature. We reported a case of a 65-year-old patient with an isolated chronic anemic syndrome secondary to megaloblastic vitamin B12 deficiency anemia treated with vitamin B12 therapy by injection. The evolution was marked three months after treatment by the an ischemic cerebrovascular accident and thrombocytosis. Additional investigations confirmed essential thrombocythemia. The patient was put under hydroxyuria and an anticoagulant treatment with a good evolution.
 
Keywords: 
Megaloblastic anemia; Thrombocytosis; Essential thrombocythemia; Thrombosis
 
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