1 Department of Biology, Laboratory of Biology, Faculty of Sciences, Gamal Abdel Nasser University of Conakry (Commune of Dixinn) BP: 1147 Republic of Guinea.
2 Faculty of Health Sciences and Techniques, Department of Medicine, Chair of Fundamental Sciences, Gamal Abdel Nasser University of Conakry, PO Box: 1147 Republic of Guinea
3 Leprology Centrer of Damakhania, Municipality of Kindia, Republic of Guinea.
Research Article
World Journal of Advanced Research and Reviews, 2022, 16(02), 309–317
Article DOI: 10.30574/wjarr.2022.16.2.1121
Received on 25 September 2022; revised on 31 October 2022; accepted on 03 November 2022
Introduction: Pulmonary tuberculosis is an infectious disease of bacterial origin caused by the bacillus Koch or BK or Mycobacterium tuberculosis. It is a contagious disease that usually attacks the lungs, but also other organs of the human body.
Objective: To contribute to the improvement of health care for patients with pulmonary tuberculosis in the city of Kindia.
Methods: This is a prospective and descriptive cross-sectional study lasting 3 months, from 03 February to 03 May 2021.
Results: Out of 301 patients received at the Leprosarium laboratory, 51 patients were diagnosed positive, i.e. 17%, against 250 negative cases, i.e. 83%. All 51 TB patients had low haemoglobin, i.e. 100%, 45% had low MCHT, 21% hyponeutrophilia versus 49% hyperleukocytosis, 35% hyperlymphocytosis and 10% hyperneutrophilia. However, all other haematological parameters were normal with the following anaemic typology: 59% frustrated anaemia and 41% moderate anaemia; 41% of patients had Microcytic and Hypochromic anaemia, compared to 59% patients with Normocytic and Normochromic anaemia. The male sex is the most represented with 71% against 29% for the female sex, the married are the most represented with 57% followed by the single with 43%, the workers are the most affected with 37% followed by the commercial agents with 21% and the pupils/students with 10%. Administrative staff are the least represented with 4%. All age groups are affected by the disease, but with a high rate among those aged between 21 and 40 years, i.e. 57%, followed by those aged 20 years or less, i.e. 23%. The age group least affected is 41 years and over, i.e. 10%. Almost all of Kindia's neighbourhoods are affected by the disease but with different rates. The districts of Manquepas and Abattoir with 8 cases each, i.e. 16%, are the most affected. They are followed by the districts of Sambaya with 11%, the rural commune of Friguiagbé with 9% and the districts of Foulémodouyah and Yéwolé with 7% each. The other districts each have 4%.
Conclusion: Pulmonary tuberculosis is a major public health problem and to improve patient management, haematological profiling is necessary.
Mycobacterium tuberculosis; Haematology; Epidemiology; Leprosarium; Kindia
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Taliby Dos Camara, Abdoulaye Makanéra, Lamine Bérété and Mohamed Bangoura. Epidemiology and impact of Mycobacterium tuberculosis on haematological parameters in patients in the city of Kindia (Republic of Guinea). World Journal of Advanced Research and Reviews, 2022, 16(2), 309-317. Article DOI: https://doi.org/10.30574/wjarr.2022.16.2.1121