Afyon Kocatepe University, Faculty of Science and Arts, Department of Chemistry, 03200, Afyonkarahisar, Turkey.
Research Article
World Journal of Advanced Research and Reviews, 2023, 20(03), 492-502
Received on 20 September 2023; revised on 01 November 2023; accepted on 03 November 2023
Total phenolic content, total antioxidant capacity, radical scavenging activity, prominent enzyme inhibitory properties, bioelement concentration and fatty acid content were determined qualitatively and quantitatively. methanol and acetone extracts of Polygonum afyonicum. The DPPH radical scavenging effect of the plant was found to be significantly different (p˂0.05) than the synthetic antioxidant butylated hydroxy toluene in the acetone extract with total phenolic content. The total antioxidant capacity of the acetone extract was higher than the methanolic extract total antioxidant status. The enzyme-inhibiting properties of acetone extract are also exceptionally high. It was found to inhibit acetylcholine esterase (86.97±3.76%) and exhibited inhibition activity as much as the standard substance galantamine (87.78±2.59%). In addition, it is seen that the tyrosinase enzyme inhibiting effect is high. Among the determined bioelements, those with the highest concentrations are Ca, K and Mg. It also contains elements (Cu, Fe, Mn and Zn) which are included in the antioxidant enzyme structure. Palmitic acid (42.5%), 1-octadecanol (9.2%) and myristic acid (7.1%) were found the most in the content of essential fatty acids and components. As a result, it was determined that the acetone extract of Polygonum afyonicum showed more antioxidative properties. The species is also prominent with its neurodegenerative effects. In addition, there is a need for structural illumination studies to reveal the metabolites responsible for biological activity by determining the phytochemicals contained in the species
Polygonum afyonicum; Antioxidant; Essential oil; Bio-element; Enzyme inhibition
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Aksoy L. Enzyme inhibitory effects, antioxidant properties, minerals and essential oils of Polygonum afyonicum. World Journal of Advanced Research and Reviews, 2023, 20(3), 492-502. Article DOI: https://doi.org/10.30574/wjarr.2023.20.3.2118