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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in April 2026 (Volume 30, Issue 1) Submit manuscript

The efficiency of high flow nasal cannula for respiratory support in adults in the intensive care unit when compared to regular oxygen, non-invasive ventilation, or non-invasive positive pressure ventilation: A systematic review

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  • The efficiency of high flow nasal cannula for respiratory support in adults in the intensive care unit when compared to regular oxygen, non-invasive ventilation, or non-invasive positive pressure ventilation: A systematic review

Fahad Bader AlGhounaim 1, *, Fahad Yahya Alzahrani 2, Faisal Alshammari 3, Ahmad Abdulrazak Al Dulaijan 4, Munirah Abdulrahman Almulhim 5, Rawan Fayez Alatigue 6, Mohammad Hassan Al Khalifa 7, Sarah Jaffer AL Ahmed 8, Adnan Khalifa Bunayan 8, Nada Mosa Almosa 9 and Hala Michal Alenazi 7

1 Home Health Care Department, King Abdulaziz Hospital, NGHA,Al-Ahsa, Saudi Arabia.
2 Anesthesia Department, Imam Abdulrahman Bin Faisal Hospital, NGHA, Dammam, Saudi Arabia.
3 Respiratory Therapy Department, Imam Abdulrahman Bin Faisal Hospital, NGHA, Dammam, Saudi Arabia.
4 Emergency Department Imam Abdulrahman Bin Faisal Hospital, NGHA, Dammam, Saudi Arabia.
5 Respiratory Care Department, Imam Abdulrahman Bin Faisal Hospital, NGHA, Dammam, Saudi Arabia.
6 Emergency Medicine Consultant, Emergency Department, Imam Abdulrahman Bin Faisal Hospital, NGHA, Dammam, Saudi Arabia.
7 Physical Therapist, Physiotherapy department, Imam Abdulrahman Bin Faisal Hospital, National Guard, Dammam, Saudi Arabia.
8 Physiotherapy technician, Physiotherapy Department, Imam Abdulrahman Bin Faisal Hospital, NGHA, Dammam, Saudi Arabia.
9 Senior Health Administration Specialist, Department of Risk Management, King Saud University, Riyadh, Saudi Arabia.
Review Article
World Journal of Advanced Research and Reviews, 2023, 19(02), 1588-1594
Article DOI: 10.30574/wjarr.2023.19.2.0897
DOI url: https://doi.org/10.30574/wjarr.2023.19.2.0897
Received on 11 May 2023; revised on 24 August 2023; accepted on 27 August 2023
Objective We aimed to compare the effectiveness of HFNC to NIV or NIPPV, conventional oxygen treatments, for respiratory support in adult intensive care unit patients.
Method: In compliance with The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guideline, this systematic review study was carried out. We looked through Google Scholar, Cochrane, PubMed, and electronic databases to find randomized controlled trials that were released between 2017 and 2023.
Result and conclusion: Five randomized controlled trials (with different primary outcomes: hospital length of stay, PaO2/FIO2 ratio, post-extubation vital signs, ABG, respiratory failure three days after extubation, and 28-day mortality rate) were included in this systematic review. Among non-hypercapnic patients at high risk of extubation failure, HFNC may be more advantageous than standard oxygen in delaying the onset of respiratory failure; in terms of vital signs and ABGs, HFNC is a viable replacement for NIV in the weaning of hypercapnic COPD patients; additionally, HFNC improved patient comfort and secretion clearance.
 
High flow nasal cannula; Respiratory support; Noninvasive ventilation; Intensive care unit
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-0897.pdf

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Fahad Bader AlGhounaim, Fahad Yahya Alzahrani, Faisal Alshammari, Ahmad Abdulrazak Al Dulaijan, Munirah Abdulrahman Almulhim, Rawan Fayez Alatigue, Mohammad Hassan Al Khalifa, Sarah Jaffer AL Ahmed, Adnan Khalifa Bunayan, Nada Mosa Almosa and Hala Michal Alenazi. The efficiency of high flow nasal cannula for respiratory support in adults in the intensive care unit when compared to regular oxygen, non-invasive ventilation, or non-invasive positive pressure ventilation: A systematic review. World Journal of Advanced Research and Reviews, 2023, 19(2), 1588-1594. Article DOI: https://doi.org/10.30574/wjarr.2023.19.2.0897

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