Effect of natural binder (okra, wheat, fragrantmanjak) concentration on thehardness and disintegration time of tablet
Department of Pharmaceutics, SMBT College of Pharmacy, Dhamangaon, Igatpuri, Nashik, Maharashtra, India.
Review Article
World Journal of Advanced Research and Reviews, 2022, 16(03), 264-269
Article DOI: 10.30574/wjarr.2022.16.3.1325
Publication history:
Received on 01 November 2022; revised on 04 December 2022; accepted on 07 December 2022
Abstract:
Binders are added in tablet formulation to increase the inter-particulate bonding strength with in the tablet. Binders are promoting the ingredient in a tablet to mix together.The main aim of this work to formulate a new excipient that is fragrant manjakfor future use as binding agent in tablet formulation, also check their effect on tablet concentration and disintegration time. Binder is employed to impact cohesiveness to the granules. Natural binder like different starch, gum, mucilage, dried fruit possesses binding capacity as well as some other properties like filter, disintegration and natural polymer are safe and economical than polymer like PVP.In this research work we evaluate the adhesion ability of fragrant manjak which had a good property as tablet binder. By this purpose fragrant manjak used as binder. Estimate for their properties including hardness, friability and disintegration rate. The prepared by fragrant manjak having a good disintegration time. These study concluded that fragrant manjak having a good binding ability. It could be used as binder in pharmaceutical industries.
Keywords:
Binder; Excipient; Gelatin; Okra; PVP; Starch
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