Effect of GERD on response to asthma treatment: A literature review

Lea Wiraputri Yohanes 1, Alfian Nur Rosyid 2, *, Muhammad Miftahussurur 3 and Arief Bakhtiar 2

1 Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
2 Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
3 Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
 
Review Article
World Journal of Advanced Research and Reviews, 2024, 24(03), 1675-1678
Article DOI: 10.30574/wjarr.2024.24.3.3834
 
Publication history: 
Received on 05 November 2024; revised on 16 December 2024; accepted on 18 December 2024
 
Abstract: 
Asthma and Gastroesophageal Reflux Disease (GERD) are two conditions that are often found together, with the prevalence of GERD in asthma patients being higher than in the general population. The pathophysiological relationship between these two conditions is complex and influences each other. GERD can worsen asthma symptoms, increase the frequency of exacerbations, and reduce the effectiveness of asthma treatment. On the other hand, asthma can also worsen GERD symptoms through the mechanism of increased intra-abdominal pressure and the side effects of certain asthma medications. This literature explores pathophysiological mechanisms, the influence of GERD on asthma treatment, and management strategies that can improve asthma control. However, further research is needed to clarify the mechanism of the relationship between these two conditions and optimize treatment strategies.
 
Keywords: 
Asthma; GERD; Relationship; Treatment; Management
 
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