Drugs and their potential teratogenic effect: A literature review
1 General Physician, Universidad Libre, Barranquilla, Colombia.
2 Pediatrician, Universidad Libre, Barranquilla, Colombia.
3 General Physician, Universidad de Cartagena, Colombia.
4 General Physician, Universidad del Sinú, Cartagena, Colombia.
5 General Physician, Corporacion Universitaria Rafael Nuñez, Cartagena, Colombia.
Review Article
World Journal of Advanced Research and Reviews, 2024, 24(02), 2627–2631
Article DOI: 10.30574/wjarr.2024.24.2.3531
Publication history:
Received on 09 October 2024; revised on 22 November 2024; accepted on 24 November 2024
Abstract:
When addressing the etymological meaning, the word teratogenesis denotes gross or "monstrous" malformations, it is currently accepted that teratogenesis is related to any defect or alteration of embryo-fetal development, whether at the functional or structural level. In general, for gross structural defects to occur, the noxa or offending substance must act on a specific period of embryonic development, which is usually at the end of the second week from conception and up to approximately 8 weeks after conception. During this critical period, organs are forming, and teratogens can produce malformations that are usually apparent at birth.
Keywords:
Pregnancy; Drug use; Teratogenic effects
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