Department of Pulmonology, AR-RAZI Hospital, MOHAMMED VI University Hospital, LRMS Laboratory, Faculty of Medicine and Pharmacy of Marrakech, Cadi Ayyad University, Marrakech, Morocco.
World Journal of Advanced Research and Reviews, 2026, 30(01), 2016-2018
Article DOI: 10.30574/wjarr.2026.30.1.1028
Received on 10 March 2026; revised on 18 April 2026; accepted on 20 April 2026
Background: Cat-scratch disease (CSD) and tuberculous lymphadenitis are the primary causes of chronic granulomatous lymphadenopathy. Distinguishing between them is challenging when necrosis is present on histopathology.
Case Report: A 15-year-old girl presented with cervical lymphadenopathy and constitutional symptoms. Despite initial suspicion of tuberculosis due to necrotic granulomas, tests including QuantiFERON-TB Gold, GeneXpert, and cultures were negative. The diagnosis of CSD was confirmed by positive Bartonella henselae serology and the recent acquisition of a kitten.
Conclusion: CSD can histologically and clinically mimic tuberculous lymphadenitis. A thorough environmental history and serology are essential to avoid diagnostic errors in endemic regions.
Necrotic granuloma; Cat-scratch disease Bartonella henselae; Tuberculous lymphadenitis; Differential diagnosis; Cervical lymphadenopathy
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A. KANDIL, C. RACHID, M. IJIM, O. FIKRI and L. AMRO. The diagnostic trap of necrotic granulomas where cat-scratch disease mimics tuberculous lymphadenitis in an adolescent. World Journal of Advanced Research and Reviews, 2026, 30(01), 2016-2018. Article DOI: https://doi.org/10.30574/wjarr.2026.30.1.1028