Determination of trace amount of some drugs as in its pure form and in its Pharmaceutical Preparations by using different spectroscopic methods

Furqan kifah kadhim 1, H. A. Alsailawi 2, *, Mustafa Mudhafar 3 and K. M. Ruaa 4

1 Department of Anesthesia Techniques, Alsafwa University College, Kerbala, Iraq.
2 Department of Biochemistry, Faculty of Medicine, University of Kerbala, 56001, Karbala, Iraq.
3 Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ahl Al Bayt, 56001, Karbala, Iraq.
4 Department of Anesthesia and Intensive Care Techniques, Faculty of Al TAff Collage, Karbala, 56001, Iraq.
 
Review Article
World Journal of Advanced Research and Reviews, 2023, 18(01), 528–542
Article DOI: 10.30574/wjarr.2023.18.1.0390
 
Publication history: 
Received on 31 January 2023; revised on 08 April 2023; accepted on 11 April 2023
 
Abstract: 
The present study includes analytical methods for determination of the drugs Chlorpromazine hydrochloride (CPZ) and trifluoperazine hydrochloride (TFPH) in some pharmaceuticals using molecular absorption, indirect AAS, in addition to investigating complexes obtained throughout. Chlorpromazine hydrochloride  and trifluoperazine hydrochloride are widely used for the treatment of schizophrenia. Synthetic formulas for the prepared drug complexes were proposed through the results of the molar ratios of the combination between the drug and each of copper, lead, chrome and iron.
 
Keywords: 
TFPH; CPZ; AAS; UV-Vis method
 
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