D-dimer levels as an associated factor for pulmonary embolism in COVID-19 patients in Critical Care Unit: A case-control study
1 Department of Critical Care, Medellin General Hospital, Medellín, Colombia.
2 Department of Hospitalized, Hospital Pablo Tobon Uribe, Medellín, Colombia.
3 Department of radiology, Hospital Pablo Tobon Uribe, Medellín, Colombia.
4 Department of Anesthesiology, Universidad CES, Medellín, Colombia.
5 Faculty of Medicine professor, CES university, Medellín, Colombia.
6 Department of Anesthesiology, Hospital General de Medellin, Medellín, Colombia.
Research Article
World Journal of Advanced Research and Reviews, 2024, 22(01), 234–240
Publication history:
Received on 24 February 2024; revised on 02 April 2024; accepted on 05 April 2024
Abstract:
Objective: Establish the association between the D-Dimer levels and pulmonary embolism (PE) in CT pulmonary angiogram (CTPA) in patients with COVID 19 in critical care.
Methodology: Case Control study in patients with diagnosis of COVID 19 in three critical care units during 2021 in Medellin. All patients had CTPA as a diagnostic method for PE.
Results: There were 135 cases and 136 controls, mean age 60 years old (IQ 51-70), 74.2 % were men. 39% had high blood pressure. Segmentary PE was found in 65.2%, lobar PE in 19.3% and 15.6% in the right or left pulmonary artery. We found that it is more likely to have PE if the D-Dimer value is more than 5000 ng/mL (ORa 7.8; IC95% 4.09-14.92).
Conclusion: D-Dimer is an independent factor that is associated with PE in patients with COVID - 19 in critical care, especially if the value is over 5000 ng/mL.
Keywords:
Pulmonary Embolism; SARS-CoV2; Thrombosis; Intensive care unit; Overweight; CT Angiography
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0