Curcumin as anti-inflammatory therapy in Covid-19 cases: A literature review

Firmansyah Adhitama Prayoga 1, Khrisna Adhityapurwita Ismanda 1, Ahda Basma Muafa 1, Rosa Arsa Maulidiyah Syahrani 2, Maftuchah Rochmanti 3 and Sakina Sakina 3

1 Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
2 Midwifery Program, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
3 Department of Anatomy, Histology, and Pharmacology, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
 
Review Article
World Journal of Advanced Research and Reviews, 2022, 15(01), 561–567
Article DOI: 10.30574/wjarr.2022.15.1.0708
 
Publication history: 
Received on 10 June 2022; revised on 12 July 2022; accepted on 15 July 2022
 
Abstract: 
The rhizome of the Curcuma longa (turmeric rhizome) plant has long been used as traditional medicine. Various studies have found that the active substance curcumin in turmeric rhizome has various effects, such as: anti-inflammatory, antifungal, and anti-bacterial for infectious disease. This review article aims to indicate the potential anti-inflammatory effects of curcumin in the treatment of Covid-19. Articles search were performed on three databases (PubMed, Sage Journals, and Nature Portfolio), in which 97 articles were found and filtered based on title, abstract, year of publication, open access, and full text review to obtain 5 relevant articles. This review explains a large potential anti-inflammatory effect of curcumin for treating Covid-19. After the effects proved for many diseases with inflammatory symptoms, similar results were also found in in-vitro testing and clinical trials on Covid-19 cases. 
 
Keywords: 
Covid-19; Curcumin; Anti-Inflammatory; Traditional medicine; Infectious disease
 
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