Covid-19 in HIV-infected patients: A report of 14 cases experience of the infectious diseases department of the University Hospital Mohamed VI Marrakech - Faculty of Medicine and Pharmacy Marrakech
Department of Infectious Diseases, University Hospital Mohamed VI, Cadi Ayyad University Marrakech, Morocco.
Research Article
World Journal of Advanced Research and Reviews, 2024, 22(02), 1566–1569
Publication history:
Received on 14 April 2024 revised on 21 May 2024; accepted on 23 May 2024
Abstract:
Objective: Evaluation of clinical, biological, radiological characteristics, therapeutic management and outcome in patients with HIV / SARS-COV-2 co-infection.
Materials and Methods: Descriptive retrospective study of 14 files of patients with HIV / SARS-COV-2 co-infection confirmed by SARS-COV-2 PCR between April 2020 and May 2022 in the infectious diseases department of the University Hospital Mohamed VI Marrakech
Results: 14 patients were included, with a sex ratio M/F: 2.5. The mean age of our patients was 40.7 years. The clinical symptoms presented by our patients were: asthenia (71%); febrile pneumonia (64.20%); anosmia (46.6%); diarrhea (28.5%); and lower limb thrombophlebitis (7.14%). The HIV status was as follows: 9 new cases (64.2%), while HIV was already present in 5 patients (35.8%). On the radiological level, 10 patients had moderate damage (72%), 3 patients had mild damage (21%), while 1 patient had severe damage (7%). Our patients' treatment changed during the study period; in particular, one group of patients was treated with the national covid-19 therapeutic protocol, while others received molnupiravir. The outcome was overall good, with a clear clinical and biological improvement; and only 4 patients died.
Conclusion: The predisposition to SARS-COV2 infection as well as the clinical presentation and evolution of Covid 19 in PLHIV do not differ from the general population.
Keywords:
Antiretroviral; SARS-COV-2; HIV; Molnupiravir; Pandemic.
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