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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in April 2026 (Volume 30, Issue 1) Submit manuscript

Conceptual and molecular docking study of newly developed antiepileptic drug cenobamate

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  • Conceptual and molecular docking study of newly developed antiepileptic drug cenobamate

Anam Ilyas 1, Shagufi Nazar 1, Nadeem Siddiqui 1, *, Ozair Alam 1, M Shaharyar 1 and Shaiza Siddiqui 2

1 Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, Hamdard Nagar, New Delhi, India-110062.
2 Department of Computer Sciences and Engineering, School of Engineering Sciences and Technology, Jamia Hamdard, Hamdard Nagar, New Delhi, India-110062.
 
Review Article
World Journal of Advanced Research and Reviews, 2023, 17(03), 281-291
Article DOI: 10.30574/wjarr.2023.17.3.0373
DOI url: https://doi.org/10.30574/wjarr.2023.17.3.0373
 
Received on 27 January 2023; revised on 06 March 2023; accepted on 08 March 2023
 
In the past two decades, there has been sudden development in antiepileptic drugs (AEDs) for the adjunctive treatment of epilepsy. CNB is a leading-edge new generation tetrazole-derived carbamate for the treatment of focal-onset epileptic seizures where the mode of action is mediated by blocking voltage-gated sodium channels and interaction with the GABAergic system. The US FDA approved CNB with new hope for superior control over seizure, better safety, and tolerability profile compared to earlier AEDs.
 
Cenobamate; Tetrazole derivative; Focal-onset seizure; Computational study; Anticonvulsant
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-0373.pdf

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Anam Ilyas, Shagufi Nazar, Nadeem Siddiqui, Ozair Alam, M Shaharyar and Shaiza Siddiqui. Conceptual and molecular docking study of newly developed antiepileptic drug cenobamate. World Journal of Advanced Research and Reviews, 2023, 17(3), 281-291. Article DOI: https://doi.org/10.30574/wjarr.2023.17.3.0373

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