A comprehensive review of green synthesis, characterization and biomedical applications of silver nanoparticle synthesized using plant extracts

Amar kumar *, Madhusudan Mahto, Shalu Priya, Shivam Thakur, Priyanka Paramanik, Renuka Verma, Padmabati Mahato and Abhijeet Bera

Department of Zoology, Jamshedpur Cooperative College, Jamshedpur, Kolhan University, Jharkhand, India.
 
Review Article
World Journal of Advanced Research and Reviews, 2024, 22(03), 1950–1977
Article DOI: 10.30574/wjarr.2024.22.3.1899
 
Publication history: 
Received on 18 May 2024; revised on 26 June 2024; accepted on 29 June 2024
 
Abstract: 
In recent years, the biogenesis of Nanoparticles has gained significant interest of the researchers. It can be attributed to the fact that Nanoparticles have varieties of application due to their unique physicochemical properties size surface morphology, charge, distribution pattern and capacity to act as a carrier of varieties of drug molecules.The present review provides a comprehensive survey of plant-mediated synthesis of AgNPs with specific focus on their applications, e.g., antimicrobial, anticancer, wound healing, drug delivery etc. as well as the characterization of nanoparticles using the techiques such as UV-Vis spectroscopy, X-Ray defraction, Fourier Transform Infrared spectroctroscopy techniquealongwith electron microscopy results. The correlation between UV-Vis peak value and the size of silver nanoparticles is also evaluated by calculating the value of correlation co efficient (r) followed by the test of hypothesis (t-test). Due to the eco-friendly nature of green synthesis technique of formation of nanoparticle using plant extract, there is a wide scope of investigation in this field. The adaptability and prospective applications of green AgNPs in the biomedical industry offer a creative substitute that can ameliorate the drawbacks of conventional systems. This indicates that green nanotechnology holds great promise for the future of medicine, since it may create low- or non-toxic nanomaterials through sustainable methods, leading to ongoing advancements towards a safer and better world.
 
Keywords: 
Nanoparticle; Green synthesis; TEM; DLS; Drug delivery; Antibacterial; Anticancerous
 
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