Comparative analysis of the antimicrobial activity of copper and copper oxide nanoparticles against Botrytis cinerea

Rohit Rawat 1, *, Akanksha Kashyap 2, Laksh Ivane 3, Prachi Sharma 3 and Pooja Gupta 3

1 Director, HARI Lifesciences, Bhopal, India.
2 Head of Academics, HARI Lifesciences, Bhopal, India.
3 Research Scholar. Babulal Gaur Govt. PG College BHEL Bhopal, India.
Research Article
World Journal of Advanced Research and Reviews, 2024, 22(03), 043–048
Article DOI: 10.30574/wjarr.2024.22.3.1622
Publication history: 
Received on 16 April 2024; revised on 25 May 2024; accepted on 28 May 2024
Botrytis cinerea, an omnipresent fungal pathogen, poses noteworthy challenges to various agricultural crops worldwide. The emergence of nanotechnology offers promising solutions to combat such pathogens. This study investigates the antimicrobial efficacy of copper and copper oxide nanoparticles against Botrytis cinerea. The comparative analysis entails the synthesis of both nanoparticle types followed by demanding evaluation of their antimicrobial activity through various assays including growth inhibition test. Factors such as nanoparticle size, concentration, and exposure duration are systematically varied to elucidate their influence on efficacy. It is discovered that copper oxide nanoparticles have greater antifungal efficacy than copper nanoparticles against Botrytis cinerea. The study revealed that the highest concentration of copper and copper oxide nanoparticles (10-3) had the greatest inhibitory effect on Botrytis cinerea, with OD values of 0.921 and 0.856 concurrently. In contrast, the control group, which did not contain any copper or copper oxide nanoparticles, had the highest mycelial growth inhibition, with an optical density of 1.010. The results showed that the optical densities of copper and copper oxide nanoparticles at concentrations of 10-6 were, respectively, 0.965 and 0.907. On the other hand, concentrations of copper and copper oxide nanoparticles at 10-9 serial dilution resulted in optical densities of 0.982 and 0.892, respectively. The findings contribute to a comprehensive understanding of the applicability of copper and copper oxide nanoparticles as alternatives to conventional fungicides in controlling Botrytis cinerea infections, thereby offering sustainable solutions for agricultural disease management.
Botrytis cinerea; Copper nanoparticles; Copper oxide nanoparticles; Optical density; Antimicrobial activity
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