Clinical view on adverse drug reactions, pharmacovigilance in India and role of clinical pharmacist

Sughosh Vishweshwar Upasani 1, *, Manali Sughosh Upasani 2, Ansari Imtiyaz Ahmed Tufail Ahmed 3, Nilesh Subhashchandra Jain 4 and Punam Rajendra Pal 5, 6

1 Department of Pharmacology and Clinical Pharmacy, SES’s R. C. Patel Institute of Pharmacy, Shirpur, 425405, Dhule, Maharashtra, India.
2 Shri Mohiniraj Institute of Classical Music and Research, Shirpur, 425405, Dhule, Maharashtra, India.
3 Department of Clinical Pharmacy and Physiology, DCS’s Institute of Pharmacy, Dhule, 424002, Maharashtra, India.
4 Department of Pharmacology and Physiology, JES’s College of Pharmacy, Nandurbar, 425412, Maharashtra, India.
5 Department of Pharmacy, Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu, Churu Road, Vidyanagari, Churela, Rajasthan-333001, India.
6 Mega Life Sciences Public Ltd. Mumbai, Maharashtra, India.
 
Review Article
World Journal of Advanced Research and Reviews, 2021, 10(03), 042–047
Article DOI: 10.30574/wjarr.2021.10.3.0233
 
Publication history: 
Received on 14 April 2021; revised on 04 June 2021; accepted on 07 June 2021
 
Abstract: 
An Adverse Drug Reaction (ADRs) is still a challenge in modern healthcare, increasing complication of therapeutics, an elderly populace and increasing multimorbidity. Pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other medicine/vaccine related problem. This article is having objective of evaluating the pharmacist perception about Pharmacovigilance and ADRs monitoring through ample literature review. In India pharmacovigilance activity begins in 1986 with ADR monitoring system under supervision of drug controller general of India. The prescribed National Pharmacovigilance Program was commence in 2005; with unsuccessful attempt in 1998, and renamed as Pharmacovigilance Program of India (PvPI) in 2010. Adverse drug reactions monitoring has become an essential part to be executed together with other health-care services for a safe use of medicines. Pharmacist can play an important role in evaluation of ADRs. Pharmacist – drug expert- having abundant knowledge of pharmacological action, pharmaco-therapeutics, adverse reactions, and disease pathophysiology, can make the drug therapy safer.
 
Keywords: 
Adverse drug reaction; Pharmacovigilance; Clinical Pharmacist; India; Modern healthcare
 
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