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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in April 2026 (Volume 30, Issue 1) Submit manuscript

Causes and methods of preventing cytokine storm in immuno-oncology

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  • Causes and methods of preventing cytokine storm in immuno-oncology

Yulii Honskyi *

President in Honskyi Scientific INC.
 
Review Article
World Journal of Advanced Research and Reviews, 2024, 23(03), 2352-2358
Article DOI: 10.30574/wjarr.2024.23.3.2886
DOI url: https://doi.org/10.30574/wjarr.2024.23.3.2886
 
Received on 10 August 2024; revised on 17 September 2024; accepted on 19 September 2024
 
Cytokine storm is an excessive immune response that can occur when using immunotherapy in oncology, especially in the case of the use of immune checkpoint inhibitors and other methods that enhance immune activity. The main causes of cytokine storm are hyperactivation of the immune system associated with excessive production of proinflammatory cytokines, which can lead to severe systemic inflammatory reactions and organ damage. Among the methods of preventing cytokine storm, careful selection and monitoring of therapy, the use of immunomodulators, as well as the development of biomarkers to predict the risk of its occurrence are distinguished. The use of combined therapeutic approaches, as well as monitoring the condition of patients and prompt response to early signs of an inflammatory reaction are key strategies in reducing the risk of developing a cytokine storm in immuno-oncology.
 
Cytokine Storm; Immunooncology; Immune Control Points; Inhibitors; Inflammation; Immunomodulation; Therapeutic Strategies; Biomarkers.
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2024-2886.pdf

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Yulii Honskyi. Causes and methods of preventing cytokine storm in immuno-oncology. World Journal of Advanced Research and Reviews, 2024, 23(3), 2352-2358. Article DOI: https://doi.org/10.30574/wjarr.2024.23.3.2886

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