A case report of nonepisodic angioedema with eosinophilia in a young Japanese female followed up with serum cytokines and immunoglobulins

Masaaki Minami 1, * and Takefumi Suzuki 2

1 Department of Bacteriology, Nagoya City University, Graduate School of Medical sciences, Nagoya, Japan.
2 Suzuki Clinic, Nishio, Japan.
 
Case Study
World Journal of Advanced Research and Reviews, 2022, 13(01), 420–423
Article DOI: 10.30574/wjarr.2022.13.1.0038
 
Publication history: 
Received on 08 December 2021; revised on 12 January 2022; accepted on 14 January 2022
 
Abstract: 
NEAE (Nonepisodic angioedema associated with eosinophilia) is a relatively common allergic disease in East Asia in which angioedema is confined to the extremities, is transient and does not recur, and is not accompanied by fever or highly elevated IgM. In this study, we report a case of NEAE disease with edema of the extremities in a young female who was able to be followed up with serum cytokines and serum immunoglobulins as biomarkers. Our results suggest that not only clinical findings but also serum biomarkers are useful in monitoring the disease status of NEAE.
 
Keywords: 
NEAE; Biomarker; Cytokine; Immunoglobulin
 
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