Cardiovascular disorders in a patient with Fabry disease: A serious prognostic factor
Cardiology Department ARRAZI Hospital, Mohammed VI University Hospital Marrakech Morocco
Case Study
World Journal of Advanced Research and Reviews, 2023, 20(02), 900–907
Article DOI: 10.30574/wjarr.2023.20.2.2093
Publication history:
Received on 03 September 2023; revised on 12 November 2023; accepted on 14 November 2023
Abstract:
Fabry disease (FD) is an inherited rare metabolic disease caused by a mutation in the GLA gene, encoding the lysosomal enzyme alpha-galactosidase A. The disorder is a systemic disease that manifests as cerebrovascular and cardiac disease, chronic renal failure, skin lesions, peripheral neuropathy, and other abnormalities. Arrhythmias, cardiac conduction disorders, and sudden deaths in Fabry diseases represent the main prognostic factors and are usually hard to manage. We describe here the case of a 56-year-old woman followed for Fabry disease with conductive and rhythmic cardiac involvement. Our case illustrates the pivotal role of critical clinical thinking in the management of rare but treatable hereditary cardiomyopathy like Fabry disease.
Keywords:
Fabry Disease; Arrhythmias; Conduction Disorders; Cardiovascular Implantable Electronic Devices; Anticoagulation.
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0