Brown tumors revealing primary hyperparathyroidism: It still exists
1 Department of Endocrinology Diabetes and Metabolic Diseases, CHU Souss Massa, Faculty of Medicine and Pharmacy, Ibn Zohr, Agadir, Morocco.
2 Department of Endocrinology, Diabetes and Metabolic Diseases, Military Hospital, Avicenne, Marrakech, Morocco, Morocco.
3 Biosciences and Health Research Laboratory, Faculty of Medicine and Pharmacy - CADI AYYAD University Marrakech, Morocco.
4 Department of Endocrinology Diabetes and Metabolic Diseases. CHU Mohamed VI, Marrakech, Morocco.
5 Department of Rheumatology, Military Hospital, Avicenne, Marrakech, Morocco.
Research Article
World Journal of Advanced Research and Reviews, 2023, 19(01), 1126–1130
Publication history:
Received on 08 June 2023; revised on 20 July 2023; accepted on 23 July 2023
Abstract:
Hyperparathyroidism is a frequent endocrinopathy, often diagnosed at the stage of subclinical hypercalcemia by systematic calcium measurement and the advent of new parathyroid hormone measurement techniques. Brown tumors represent a late-onset, locally aggressive but potentially benign non-metastatic bone complication secondary to an abnormality of bone metabolism within the context of hyperparathyroidism. It is usually a late complication, rarely revealing. We report 2 clinical cases of primary hyperparathyroidism revealed by a brown tumor, complicated in one case by a pathological fracture. The aim of our work is to underline the importance of looking for hyperparathyroidism in every lytic lesion, given the insidious nature of this endocrinopathy, thus preventing pathological fractures and improving functional quality of life.
Keywords:
Brown tumors; Primary hyperparathyroidism; Parathyroid adenoma; Pathological fracture
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0