Biological synthesis and characterization of copper oxide nanoparticles using aqueous Psidium guajava leave extract and study of antibacterial activity of the copper oxide nanoparticles on Escherichia coli and Staphylococcus aureus

Samuel Paul 1, *, Akintunde Sheyi 2, Iliya Daniel Bangu 3, Sani Idris Abubakar 3 and Muawiyya Muazu Muhammad 4

1 Department of Chemical Sciences, Federal University, Kashere P.M.B 0182 Gombe State Nigeria. 
2 Department of Science Laboratory Technology, Federal College of Forestry Jos, P.M.B 2019, Plateau State, Nigeria.
3 Department of Soil Science, Federal University, Kashere P.M.B 0182 Gombe State Nigeria.
4 Department of Forestry Management and Research, Upland Forest Research Station Gombe, P.M.B 5054 Gombe State Nigeria.
 
Research Article
World Journal of Advanced Research and Reviews, 2021, 09(01), 114-120
Article DOI: 10.30574/wjarr.2021.9.1.0513
 
Publication history: 
Received on 23 December 2020; revised on 02 January 2021; accepted on 03 January 2021
 
Abstract: 
Nanobiotechnogy has been developed to synthesized copper oxide nanoparticle. This was carried out biologically using leaf extract of Psidium guajava as a reducing and stabilizing agent. Optical property showed a color change from dark brown to gold- yellow after the addition of leaf extract. The possible functional group in the plant extract responsible for the reduction of CuONps was identified as belonging to alkyl halide group by FT-IR analysis. UV- visible spectra of copper oxide nanoparticle showed a surface plasmon resonance peak at 390nm. The biologically synthesized copper nanoparticles were tested for antibacterial activity against two human pathogens viz, Escherichia coli and Staphylococcus aureus. Biosynthesized copper nanoparticle showed clear zone of inhibition or better activity against Escherichia coli and Staphylococcus aureus.
 
Keywords: 
Psidium guajava; Nanoparticles; Synthesis; UV-VIS; FT-IR
 
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