1Biologist, Head of the Research and Training Unit (URF) and Head of Department, Laboratories of the National Reference University Hospital (CHU-RN) of N’Djamena. Centre Hospitalier Universitaire de Référence Nationale (CHU-RN) de N’Djamena (Chad).
2Faculty of Human Health Sciences (FSSH), University of N’Djamena, BP 1117 N’Djamena, Chad.
3Laboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food(LaBESTA) / Doctoral School of Sciences and Technologies, University of Ouaga 1 Joseph KI-ZERBO, 03 BP 7021 Ouagadougou 03, Burkina Faso.
Research Article
World Journal of Advanced Research and Reviews, 2021, 10(01), 381-396
Article DOI: 10.30574/wjarr.2021.10.1.0189
Received on 23 March 2021; revised on 28 April 2021; accepted on 30 April 2021
The aim is to assess the level of contamination of wound bacteria in operated patients in the surgical departments of the National Reference University Hospital (CHURN) of N’Djamena.
From August 1, 2018 to August 1, 2019, an observational culture study on wound pus was carried out in patients operated on from the surgical services of the N’Djamena CHURN according to standard methods of medical microbiology.
Of the 1092 patients operated on, 565 patients were released within a normal period of hospitalization and 527 in contact with the pathogens were maintained. Significant differences were observed between the proportions of positive (86%) and sterile (14%) cultures; female (30.36%) and male (69.63%) operated subjects with probabilities of 0.02 and 0.001 respectively.
Escherichia coli were the most common germs (32.7%), followed by Staphylococcus spp (20.9%). The bacteria isolated were resistant to beta-lactam antibiotics at an average rate of 40%, only imipenem, a last-resort antibiotic, was very sensitive (99.5%).
In view of these results, we recommend that prescribers avoid prescribing antibiotics without laboratory evidence for fear of losing the beta-lactams permanently.
Infection; Surgical site, Antibiotic; Resistance; N’Djamena.
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Bessimbaye Nadlaou, Djimadoum Mbanga, Issakou Bakarnga-Via, Claude Oualé, Nicolas Barro, Abdelsalam Tidjani and Choua Ouchemi. Biochemical profile and resistance phenotype of bacteria isolated from the operating site departments of the National Reference University Hospital of N’Djamena. World Journal of Advanced Research and Reviews, 2021, 10(1), 381-396. Article DOI: https://doi.org/10.30574/wjarr.2021.10.1.0189