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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in April 2026 (Volume 30, Issue 1) Submit manuscript

Benign outcomes of metformin for various diseases: A review

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  • Benign outcomes of metformin for various diseases: A review

SANTHOSH G 1, *, NITHISHWAR M 1 and FATHIMA BASHEERA M 2

1 Doctor of Pharmacy, Department of Pharmacy practice, Arulmigu kalasalingam college of Pharmacy, Virudhunagar, Tamilnadu, India – 626126.
2 Assistant Professor, Department of Pharmacy Practice, Arulmigu kalasalingam college of Pharmacy, Virudhunagar, Tamilnadu , India – 626126.
 
Review Article
World Journal of Advanced Research and Reviews, 2023, 20(01), 278-286
Article DOI: 10.30574/wjarr.2023.20.1.2036
DOI url: https://doi.org/10.30574/wjarr.2023.20.1.2036
 
Received on 23 August 2023; revised on 01 October 2023; accepted on 04 October 2023
 
Metformin is the most popularly prescribed first-line drug in the management of type 2 diabetes mellitus. Metformin exerts different effects such as anti- hyperglycemic effect, analgesic effect in the management of musculoskeletal pain and anti-depressant effect in depression management, cardio protective and neuroprotective effects in the cardiovascular system and central nervous system. Nrf2 is the factor responsible for enhancing the anti-oxidative effects of metformin. Metformin exerts its anti-proliferative effect through the suppression of tumor development and modifies the surroundings of the tumor.
 
Metformin; Diabetes mellitus; AMPK activation; Pain management; PCOS; Depression.
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-2036.pdf

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SANTHOSH G, NITHISHWAR M and FATHIMA BASHEERA M. Benign outcomes of metformin for various diseases: A review. World Journal of Advanced Research and Reviews, 2023, 20(1), 278-286. Article DOI: https://doi.org/10.30574/wjarr.2023.20.1.2036

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