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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

An Ayurvedic intervention in the management of Pramehajanya Upadrava Vis-a-Vis Diabetic Nephropathy with Special reference to Microalbuminuria: A Pilot Study

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  • An Ayurvedic intervention in the management of Pramehajanya Upadrava Vis-a-Vis Diabetic Nephropathy with Special reference to Microalbuminuria: A Pilot Study

Viraj V. Shukla 1, *, Shrikant G. Deshmukh 2 and Sonali V. Shukla 3

1 Department of Kayachikitsa, LKR Ayurveda College Gadhinglaj, Kolhapur, Maharashtra. India.
2 Department of Kayachikitsa c.s.m.s.s. Ayurveda College, Cha. Sambhaji Nagar Maharashtra, India.
3 Department of Kriya Sharir, LKR Ayurveda College Gadhinglaj, Kolhapur, Maharashtra, India.
 
Research Article
World Journal of Advanced Research and Reviews, 2024, 23(03), 1199-1204
Article DOI: 10.30574/wjarr.2024.23.3.2748
DOI url: https://doi.org/10.30574/wjarr.2024.23.3.2748
 
Received 27 July 2024; revised on 08 September 2024; accepted on 10 September 2024
 
Diabetes Mellitus is a multifactorial Clinical Syndrome affecting multiple systems and Organs. Type-1 DM is an autoimmune disease Characterized by antibody mediated and cell mediated destruction of pancreatic cells while Type-2 DM is Characterized by relative deficiency and resistance to insulin action. One of the micro vascular Complication of Diabetes mellitus is Diabetic Nephropathy also known as Diabetic Kidney disease (D.K.D.) leading to End Stage Renal disease (E.S.R.D.) in due course of time.
In Ayurveda classical texts, although there is no any direct reference in prameha Chapter of renal complications, but in 'Mutraghata Chapter' few Similar Conditions are explained and hence may be Co- related with nephropathies. The disease prameha happens due to derangement into Tridoshas (three humors) and especially Vata dosha dominance in etiopathogenesis leads to Madhumeha; the nearest Co- relate of D.M.
 In the present study pre diagnosed patients of Type-2 D.M were randomly selected and Screened for microalbuminuria levels i.e. the albumin Levels in urine ranging between 30-300 mg/24 hr. urine. An Ayurvedic drug 'Gokshura - Brihatyadi Kashaya' was administered in the dose of 50 ml twice daily for 60 days. The subjective and objective parameters were assessed before Treatment and after completion of 60 days which shows significant reduction in both type of parameters.
 
Diabetic Nephropathy; Gokshura Brihatyad Kashayam; Complications of DM; Type 2 DM.
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2024-2748.pdf

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Viraj V. Shukla, Shrikant G. Deshmukh and Sonali V. Shukla. An Ayurvedic intervention in the management of Pramehajanya Upadrava Vis-a-Vis Diabetic Nephropathy with Special reference to Microalbuminuria: A Pilot Study. World Journal of Advanced Research and Reviews, 2024, 23(3), 1199-1204. Article DOI: https://doi.org/10.30574/wjarr.2024.23.3.2748

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