Atypical presentation of anti-Ma2-associated encephalitis mimicking diencephalic demyelinating syndrome
1 Department of Neurology, Agadir Military Hospital, Agadir, Morocco.
2 Department of Neurology, Hassan II University, Casablanca, Morocco.
3 Department of Radiology, Agadir Military Hospital, Agadir, Morocco.
4 Department of Neurology, Mohammed V Military Hospital, Rabat, Morocco.
Case Study
World Journal of Advanced Research and Reviews, 2024, 22(01), 223–225
Article DOI: 10.30574/wjarr.2024.22.1.1077
Publication history:
Received on 25 February 2024; revised on 02 April 2024; accepted on 05 April 2024
Abstract:
Anti Ma 2 encephalitis is an autoimmune encephalitis, usually paraneoplastic, characterized by isolated or combined limbic, diencephalic, or brainstem dysfunction. It most commonly affects males with testicular or small cell lung cancer, though cases have been reported in females with gynecologic malignancies [1].
We describe an unusual presentation of a paraneoplastic neurologic syndrome presenting with predominant involvement of the hypothalamus and deep grey nuclei secondary to a testicular cancer associated with anti-Ma2 antibody.
Keywords:
Paraneoplastic encephalitis; Diencephalic lesion; Autoimmunity; Anti-ma2 antibody.
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