1 Department of Medicine, Faculty of Health Sciences and Techniques, Chair of Fundamental Sciences, Gamal Abdel Nasser University of Conakry, PO Box: 1147 Republic of Guinea.
2 Biomedical laboratory, China-Guinea Friendship Hospital, Kipé, Cité des Médecins, Commune Ratoma 30 BP: 710 Conakry, Republic of Guinea.
3 Microbiology Laboratory, Department of Biology, Faculty of Sciences, and Gamal Abdel Nasser University of Conakry BP: 1147 Republic of Guinea.
4 Biomedical Laboratory of the Kankan Regional Hospital, Prefecture of Kankan, Administrative Region of Kankan, Republic of Guinea.
Research Article
World Journal of Advanced Research and Reviews, 2024, 22(02), 802-813
Received on 25 March 2024; revised on 04 May 2024; accepted on 06 May 2024
Objective: The aim of this study was to determine the tuberculosis and hepatitis B virus co-infection among people living with HIV at the Kankan Regional Hospital (HRK) in Guinea and to describe the biological and clinical signs associated to the co-infections.
Methods: It was 4 years retrospective study (January 1st, 2015-December 31st, 2018. data was collected from lab registers and hospitalization files. Results: On a total of 345 PVVH, HBsAg testing was carried out. Thus 9.3% (32/345) were co-infected with HIV/HBV with the presence of jaundice in 8.1% (28/345). All patients (100%) had oropharyngeal candidiasis (thrush). About 44.1% (152/345) of patients tested positive for tuberculosis, while 49.6% (171/345) presented with prurigo. The results of the study showed that the female gender was predominant with a sex ratio (M/F) = 0.69. The average age of the patients was 38.45±13.38 [16-80 years]. The most represented age group was ≥35 years (55.9%), followed by 25-29 years (16.8%) and 30-34 years (14.2%). More than half of the patients were married (51.6%), and singles accounted for 31.0%. On a socio-professional level, workers were in the majority (54.7%), followed by farmers (15.1%) and traders (14.5%).
Conclusion: All of these results show that the prevalence of tuberculosis and hepatitis B was high among people living with HIV at the Kankan Regional Hospital.
Co-infection; HIV; HBV; Tuberculosis; HRK; Kankan; Guinea
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Abdoulaye Makanéra, Taliby Dos Camara, Abdrhamane Seini Insa, Sidikiba Sidibé and Mamoudou Camara. Assessment of hepatitis B virus infection and tuberculosis among people living with HIV at the Kankan Regional Hospital (Republic of Guinea). World Journal of Advanced Research and Reviews, 2024, 22(2), 802-813. Article DOI: https://doi.org/10.30574/wjarr.2024.22.2.1358