Approach to resistant IVIG Kawasaki disease in children
1 General Pediatric Ward, University Hospital Center “Mother Tereza”, Tirana, Albania.
2 Pediatric Infectious Disease Ward, University Hospital Center “Mother Tereza”, Tirana, Albania.
3 University Hospital Center “Mother Tereza”, Tirana, Albania.
4 American Hospital Center, Pristina, Kosovo.
Case Study
World Journal of Advanced Research and Reviews, 2023, 19(02), 1256–1263
Publication history:
Received on 20 March 2023; revised on 26 August 2023; accepted on 28 August 2023
Abstract:
Kawasaki disease (KD) is an acute febrile illness of early childhood characterized by vasculitis of the medium-sized arteries. There is no diagnostic test for KD because the cause is unknown, so diagnosis relies on the recognition of the diagnostic clinical criteria. The most feared sequela of KD is development of coronary artery abnormalities, which occur in 20-25% of untreated children. IVIG reduces this risk in 2-5% when administrated within 10 days from the onset of fever. Here is reported the case of an infant which resulted resistant to 2 consecutive doses of IVIG. Glucocorticoids are recommended as an appropriate therapy in IVIG resistant Kawasaki disease.
Keywords:
Kawasaki disease; IVIG; Glucocorticoids; Resistance; Children
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0