Aplasia cutis congenita and central nervous system malformations on a multiple pregnancy with fetus papyraceus: Case report
1 Department of Pediatrics, Faculty of health sciences, Militar Nueva Granada University, Hospital Militar Central, Bogota, D.C, Colombia.
2 Neonatal Intensive Care Unit, Hospital Militar Central, Bogota, D.C., Colombia.
Case Study
World Journal of Advanced Research and Reviews, 2023, 20(01), 480–485
Publication history:
Received on 31 August 2023; revised on 09 October 2023; accepted on 11 October 2023
Abstract:
A fetal death in utero causes a prothrombotic environment due to abnormal placental anastomoses with hypoperfusion, which determines multisystem malformations, including dermal and subcutaneous involvement such as aplasia cutis and a central nervous system (CNS) abnormalities. We present the case of a quadruple pregnancy with death of a fetus at week 16, from which 3 live newborns were obtained, twin #1 with aplasia cutis type V. Twin #2 who did not present complications or associated malformations and twin # 3 with radiological documentation of dysgenesis of the corpus callosum. Based on literature, there is a relationship between chorionicity and the history of a papyraceous fetus and the multisystemic congenital malformations.
Keywords:
Vanishing twin syndrome; Fetus papyraceus; Aplasia cutis congenita; Multiple pregnancy; Fetal death; Prematurity.
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