Antiproliferative activity of marine brown algae-derived compounds: A review

Luane Oliveira Araújo 1, Jessyca Karoline de Oliveira Silva 2, Beatriz Alves de Aguiar 2, Julliene Larissa dos Santos Bezerra 2, Aline de Queiroz Rodrigues 2 and Fernanda Paulini 2, *

1 Department of Pharmacy, Faculty of Health, University of Brasília, Brasília, Brazil.
2 Department of Physiological Sciences, Institute of Biological Sciences, University of Brasília, Brasília, Brazil.
 
Review Article
World Journal of Advanced Research and Reviews, 2021, 11(01), 060-072
Article DOI: 10.30574/wjarr.2021.11.1.0306
Publication history: 
Received on 28 May 2021; revised on 05 July 2021; accepted on 09 July 2021
 
Abstract: 
Marine environment exploration has increased in the search for new compounds that may be attractive to the industrial field, especially for the development of drugs. Brown marine algae are part of this environment and, because of their production of secondary metabolites, they have become a possible source of bioactive compounds that have important biological actions such as anticoagulant, antioxidant and antiproliferative. However, there are still obstacles to complete knowledge about their structures and activities. This review provides key information about the isolation, composition, and structure and antiproliferative activity in vitro and in vitro of compounds derived from different brown algae.
 
Keywords: 
Marine Natural Products; Seaweeds; Antitumoral compounds; Marine biodiversity
 
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