Antioxidant activity of silver nanoparticles synthesized by hydroalcoholic extract of Triphala
1 Institute of Pharmaceutical Sciences, Shri JJT University, Chudela, Jhunjhunu 333001, Rajasthan, India.
2 Academy of Pharmaceutical Sciences, Kannur, Kerala, India.
Research Article
World Journal of Advanced Research and Reviews, 2022, 16(02), 383–388
Article DOI: 10.30574/wjarr.2022.16.2.1164
Publication history:
Received on 28 September 2022; revised on 06 November 2022; accepted on 09 November 2022
Abstract:
The aim of the present study was to investigate the in vitro antioxidant activity of hydroalcoholic extract of Triphala and its ecologically friendly synthesized silver nanoparticles. In the present study, we conducted an estimation of the extract using Hydrogen peroxide radical scavenging assay and superoxide radical scavenging assay to assess the antioxidant potential. The results were compared with the effect of standard ascorbic acid.
Primary phytochemical screening of the plant extract showed the presence of carbohydrates, alkaloids, glycosides, flavonoids, phenolics etc. The hydroalcoholic extract and its SNPs showed a concentration-dependent activity in both methods.
In the study, it was concluded that the hydroalcoholic extract of Triphala comprises pharmacologically important phytoconstituents like phenolic compounds and flavonoids which impart the potential of the extract as well as its SNPs in the modulation of oxidative stress owing to its strong antioxidant and free radical scavenging activities.
Keywords:
Antioxidant activity; Hydrogen peroxide radical scavenging assay; Superoxide free radical scavenging assay; Silver nanoparticles
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