1 Faculty of Biochemistry, Chemistry and Pharmacy, Chair of Quality Assurance of Drugs and Medications, National University of Tucumán, Tucumán, Argentina.
2 Faculty of Biochemistry, Chemistry and Pharmacy, Chair of Microbiology, Faculty of Agronomy and Zootechnics, Chair of Organic Chemistry, National University of Tucumán, Tucumán, Argentina.
Research Article
World Journal of Advanced Research and Reviews, 2022, 15(02), 661-671
Article DOI: 10.30574/wjarr.2022.15.2.0836
Received on 11 July 2022; revised on 22 August 2022; accepted on 24 August 2022\
Among berries, blueberries (Vaccinium corymbosum L.) are considered one of the main sources of phenolic compounds and are appreciated for their high antioxidant activity. Due to the apparent relationship between phytochemicals in plants to the prevention of chronic diseases, the study of the content and physiological activity of phenolic compounds and other bioactive metabolites present in blueberries is interesting.
In this work, Tucuman blueberries of the O'Neal variety were used, out of which four different extracts were obtained. One of them was obtained by sequential leaching with hydroalcoholic mixtures from frozen fresh fruits (E1), a second extract from aqueous leaching (E2), and acetone as solvent (E3). Spectrophotometric techniques were performed to quantify Total Phenols, Total Flavonoids and Anthocyanins. The extracts presented a similar quantitative profile of phenolic compounds. The antioxidant activity of the extracts obtained was evaluated using two different techniques (ABTS•+ and DPPH•). The extracts showed a free radical inhibitory activity and a similar reducing power.
Through the acute toxicity test (24h) of the organic and aqueous extracts from the blueberry on C. elegans, .it was possible to determine that the extracts under study do not show toxicity for further study.
Total phenols; Anthocyanins; Antioxidant capacity; Cytotoxicity; Vaccinium corymbosum L
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María Paola Muratore Lorenzi, Cesar Emmanuel Ale and María Alejandra Moyano. Antioxidant activity and cytotoxicity of Vacciniun corymbosum L. cultivated in Tucumán, Argentina. World Journal of Advanced Research and Reviews, 2022, 15(2), 661-671. Article DOI: https://doi.org/10.30574/wjarr.2022.15.2.0836