Antibacterial potential of Durian montong peel extract (Durian zibethinus murray) against growth inhibition of Streptococcus mutans
1 Department of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
2 Profession Student, Faculty of Dental Medicine, Universitas Airlangga, Surabaya.
3 Postgraduate Student, Faculty of Public Health, Universitas Airlangga, Surabaya.
4 Postgraduate Student, Faculty of Dental Medicine, Universitas Airlangga, Surabaya.
5 Master Program, Dental Health Science, Faculty of Dental Medicine, Universitas Airlangga, Surabaya.
6 Department of Dental Materials, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
7 Department of Dental Medicine, Faculty of Medicine, LBB University, Yemen.
Research Article
World Journal of Advanced Research and Reviews, 2024, 21(01), 2839–2846
Publication history:
Received on 16 December 2023; revised on 27 January 2024; accepted on 30 January 2024
Abstract:
Introduction: Caries is a chronic infection of tooth tissue which is experienced by 50% of the world's population. Loss of teeth due to caries can cause problems, including mastication disorders. Caries can occur due to the activity of the main bacteria, ie Streptococcus mutans (S. mutans). A solution is needed to inhibit the growth of S. mutans bacteria, one of them with montong durian peel extract (Durian zibethinus murray) which has antibacterial properties such as flavonoids, saponins, and tannins.
Purpose: Proving the antibacterial potential of montong durian peel extract against growth barriers of Streptococcus mutans.
Methods: This research is an in vitro study with a posttest only control group design. Montong durian peel extract was obtained by maceration method, and divided into concentrations of 90%, 45%, 22.5%, 11.25%, 5.625%; with replication of each concentration 6 times. The tests carried out included phytochemical tests, Minimum Inhibitory Concentration (MIC) tests and Minimum Bactericidal Concentration (MBC) tests. The data obtained was then tested statistically with ANOVA.
Results: There was a significant difference between the groups for the MIC test (p = 0.00) and for the MBC test (p = 0.00), with MIC at a concentration of 22.5%, and MBC at a concentration of 45%.
Conclusion: Montong durian peel extract has antibacterial potential that can inhibit growth of S.mutans.
Keywords:
Montong durian peel extract; Streptococcus mutans; MIC, MBC; Good health and well-being
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0