Antibacterial effect of polyphenols enriched drumstick plant leaves (Moringa oleifera) extract: A research study

Vedamurthy Joshi 1, Rajesh Kowti 2, B. Ramesh 3, Santhosh Kumar Nune 4 and Dinesha Ramadas 5, *

1 Dept. of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya District, Karnataka, India.
2 Dept. of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya District, Karnataka, India.
3 Dept. of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya District, Karnataka, India.
4 Dept. of Clinical Biochemistry, Shridevi Institute of Medical Sciences, Tumakuru, Karnataka, India.
5 Adichunchanagiri Institute for Molecular Medicine, AIMS-Central Research Laboratory, Adichunchanagiri Institute of Medical Sciences.  CORMIL & CMPAT, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya District, Karnataka, India
 
Research Article
World Journal of Advanced Research and Reviews, 2020, 08(02), 158-163
Article DOI: 10.30574/wjarr.2020.8.2.0406
 
Publication history: 
Received on 28 October 2020; revised on 03 November 2020; accepted on 06 November 2020
 
Abstract: 
Microorganisms are raising resistance against available antibiotics due to usage of antibiotics in a wrong way.  There is lot of demand for finding /searching new natural antimicrobial agents as they are inexpensive, easily available, most of them are edible and mainly non-toxic even at the rate of milligram quantity.  The aim was to study the efficiency of the anti-bacterial effect of Polyphenols enriched extract of Drum stick plant leaves (Moringa oleifera) against staphylococcus aureus. The materials involved in this study include Drum stick plant leaves, micro-organism staphylococcus aureus in the bacterial type culture collection, agar, and blood-agar plates. At 10% concentration, of Polyphenols enriched extract of Drum stick leaves had zero anti-bacterial activity, while between 20 to 25% concentrations revealed high activity against the bacteria. Thus, increased in the anti-bacterial activity was promising as the concentration augmented from 20 to 25%. The results acquired from this study points that polyphenol enriched extract of Drum stick leaves (Moringa oleifera) had antibacterial property against Staphylococcus aureus when obtained to a necessary concentration.
 
Keywords: 
Drum stick plant leaves; Moringa oleifera; Stephylococcus aureus; Anti-bacterial effect; Polyphenols enriched extracts
 
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