Antibacterial activity of Eurya acuminata DC. leaves ethanol extract against Pseudomonas aeruginosa and Staphylococcus aureus
Department of Biology, Faculty of Mathematics and Natural Science, Andalas University, 25163 Padang, West Sumatera, Indonesia
Research Article
World Journal of Advanced Research and Reviews, 2022, 16(03), 404-410
Article DOI: 10.30574/wjarr.2022.16.3.1326
Publication history:
Received on 26 October 2022; revised on 10 December 2022; accepted on 12 December 2022
Abstract:
Antibiotics as modern medicine in the treatment of infections have experienced resistance due to irrational use. Traditional medicinal plants have many chemical components that have been used to treat various diseases including skin diseases, one of them is Eurya acuminata DC. The study aimed to determine the optimum concentration of E. acuminata leaves extract against Pseudomonas aeruginosa and Staphylococcus aureus. This antibacterial test was carried out using the diffusion and dilution method. The concentrations of ethanol extract used were 20%, 40%, 60%, 80% and fresh extract. The highest antibacterial activity of E. acuminata leaves ethanol extract was by diffusion against P. aeruginosa and S. aureus were present at a concentration of 60% with an inhibition zone by 11.72 mm and 10.84 mm, respectively. The MIC and MBC values of the ethanol extract of E. acuminata leaves were not found. It was concluded that E. acuminata leaves ethanol extract might be an alternative antibacterial agent because it was able to inhibit P. aeruginosa and S. aureus.
Keywords:
Antibacterial; Ethanol extract; Eurya acuminata; Pseudomonas aeruginosa; Staphylococcus aureus
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