Alteration in prothrombin time, INR, partial thromboplastin time and platelets in type 2 diabetes mellitus, cross-sectional study- Sudan

Omer Ibrahim Abdallah Mohammed *

Omdurman Islamic University, Faculty of Medical Laboratory Sciences, Department of Hematology, Khartoum, Sudan.
 
Research Article
World Journal of Advanced Research and Reviews, 2020, 05(03), 129-133
Article DOI: 10.30574/wjarr.2020.5.3.0065
 
Publication history: 
Received on 16 March 2020; revised on 25 March 2020; accepted on 28 March 2020
 
Abstract: 
Diabetes mellitus is a common disease and it is a major cause of morbidity; several studies indicate that diabetes is a likely under reported cause of death. The goal of current study to evaluate the alteration of Prothrombin Time,Activated Partial Thromboplastin Time and Thrombocytes among in type 2 diabetes mellitus. Fifty-seven patients have diabetic and twenty healthy people considered as control. The blood coagulation parameters (PT, INR and aPTT) were measured by coagulation analyzer. Platelets was counted by hematological analyzer (Sysmex). Data analysis was performed using statistical package for social science (SPSS) software. Evaluation of patient’s data was performed using the t-test and Pearson correlation test, results with p value < 0.05 were considered as statistically significant. Our result showed with p value < 0.05 in PT, INR, aPTT and Platelet, when were compared to control group. From our finding we concluded that, diabetes mellitus is more prone to change in PT, INR, APTT and Platelet count.
 
Keywords: 
Prothrombin Time; INR; Partial Thromboplastin Time; Platelet; Diabetes Mellitus
 
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