Allergic reactions to cephalosporin antibiotics in a 15-year-old population
Faculty of Pharmacy,University of Tuzla,Bosnia and Herzegovina.
Case Study
World Journal of Advanced Research and Reviews, 2021, 12(03), 634–639
Article DOI: 10.30574/wjarr.2021.12.3.0689
Publication history:
Received on 07 November 2021; revised on 29 December 2021; accepted on 31 December 2021
Abstract:
Cephalosporin, along with penicillin, are among the least harmful antibiotics. It is widely prescribed for common infections such as bronchitis, otitis media, pneumonia and cellulitis. A contraindication for this agent is a history of penicillin allergy, due to possible cross-reactions of hypersensitivity to penicillin and cephalosporin. Hypersensitivity reactions can occur in any mode of administration and to almost all antibiotics. Hypersensitivity reactions to cephalosporin are very similar to those of penicillin. The purpose of the study was to determine whether exist reactions to cephalosporin in the study population, and to determine whether exist statistically significant differences in the occurrence of allergic reactions to cephalosporin between boys and girls of the same age and whether exist differences in the occurrence of allergic reactions between subjects in urban and rural areas. The sample consisted of 1605 respondents, the sample was randomly selected and stratified by sex, and all data were processed in the statistical program. The results of the research show that 9.1% of the total population of boys and girls aged 15 from the Tuzla Canton are allergic to some type of antibiotic. The percentage of allergic reactions to cephalosporin is statistically significantly higher in the total population of 15 - year - olds from suburban and urban settlements than among peers in rural areas. Allergic reactions to cephalosporin were not observed in the group of boys from urban and suburban settlements as well as girls from rural settlements. This research also showed that there are statistically significant differences in the occurrence of cephalosporin allergies between urban and rural respondents.
Keywords:
Cephasporin Antibiotics; Allergies; Male and Female population; Urban and Suburban area
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