Adenocortical carcinoma: A rare malignant tumor

Mohammed CHEIKH 1, 2, *, Cheikh Saad Bouh KHATRATY 1, 2, Omar TALEB 1, 2, Soufiane MELLAS 1, 2, Jalal Eddine EL AMMARI 1, 2, Mohammed Fadl TAZI 1, 2, Mohammed Jamal EL FASSI 1, 2, Moulay Hassan FARIH 1, 2 and Mustapha AHSAINI  1, 2

1 Department of Urology, Hassan II University Hospital, Fez, Morocco.
2 Faculty of Medicine, Pharmacy and Dentistry of Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
 
Case Study
World Journal of Advanced Research and Reviews, 2024, 21(02), 1430–1434
Article DOI: 10.30574/wjarr.2024.21.2.0548
 
Publication history: 
Received on 22 January 2024; revised on 19 February 2024; accepted on 21 February 2024
 
Abstract: 
Adrenocortical adenocarcinoma (ACA) is a rare malignancy that develops at the expense of the adrenal cortex. The key to its treatment lies in surgery, with complete resection of a localized form offering the best chance of cure. This article presents the case of a 68-year-old man treated for adrenocortical adenocarcinoma at the Hassan 2 University Hospital in Fez. The patient, with no notable pathological history, consulted for dizziness and abdominal pain, leading to the discovery of a malignant adrenal mass on radiological evaluation. A successful left laparotomy adrenalectomy was performed, confirming, by pathological analysis, a Weiss score 4 adenocarcinoma. Immunohistochemical results showed expression of cytokeratin AE1/AE3, while other markers were absent. The article highlights the efficacy of surgery in the treatment of localized forms of this rare tumor, while highlighting diagnostic challenges and the need for international coordination in adrenocortical adenocarcinoma research and care.
 
Keywords: 
Adenocortical Carcinoma; Case  Report; Malignant Tumor; Adrenal Cortex; Surgery; Laparotomy
 
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