A rare case of an aggressive macroprolactinoma invading the sphenoid bone, clivus and cavernous sinuses posing the differential diagnosis with chordoma

W. Douali *, Z. Ismail, S. Rafi, G. El Mghari and N. El Ansari

Endocrinology, diabetology, metabolic diseases and nutrition department CHU Mohamed VI Marrakech.
 
Case Study
World Journal of Advanced Research and Reviews, 2023, 17(03), 184–187
Article DOI: 10.30574/wjarr.2023.17.3.0115
 
Publication history: 
Received on 19 December 2022; revised on 03 March 2023; accepted on 06 March 2023
 
Abstract: 
Aggressive macroprolactinomas represent 0.4 to 4% of pituitary adenomas, they are more frequent in men, the positive diagnosis is easy, the evaluation of aggressiveness is essentially based on MRI and The treatment with dopaminergic agonist in first intention is now well established and should not be deferred apart from neurological emergency situations.
 
Keywords: 
Aggressive Macroprolactinomas; Chordoma; Hypothalamic-Pituitary MRI; Knosp's Classification; Complex Management
 
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