Plasma cell leukemia: A rare case
Hematology Laboratory, Avicenne Military Hospital, FMPM, Marrakech, Morocco.
Case Study
World Journal of Advanced Research and Reviews, 2023, 18(01), 289–293
Article DOI: 10.30574/wjarr.2023.18.1.0429
Publication history:
Received on 05 February 2023; revised on 04 April 2023; accepted on 07 April 2023
Abstract:
Plasma cell leukaemia is an extremely rare haematological malignancy with a poor prognosis.
It is defined by the presence in the circulating blood of a number of plasma cells greater than 2 giga/L or greater than 20% of the leukocytes. It presents in two forms: secondary plasma cell leukaemia complicating a known multiple myeloma, and primary plasma cell leukaemia, which is leukaemic in origin.
We report the observation of a 52-year-old Moroccan patient who presented with bone pain and general deterioration 3 months before hospitalisation.
The haemogram revealed normocytic normochromic anaemia at 8.1 g/dL and hyperleukocytosis. The blood smear showed the presence of 38% of plasma cells. The myelogram confirmed the diagnosis of APL by showing a rich marrow with 63% dystrophic plasma cells.
In this case, we emphasise the importance of careful cytological examination of the blood smear.
Keywords:
Plasma cell leukemia; Blood test; Myelogram
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0