HHV-8-associated multicentric Castleman disease with hemophagocytic syndrome in an HIV-infected patient: A case report
1 Department of Internal Medicine, Avicenne Military Hospital of Marrakech, Faculty of Medicine and Pharmacy Marrakech, Morocco.
2 Department of Radiology, Avicenne Military Hospital of Marrakech, Faculty of Medicine and Pharmacy Marrakech, Morocco.
3 Department of Pathology, Avicenne Military Hospital of Marrakech, Faculty of Medicine and Pharmacy Marrakech, Morocco.
Case Study
World Journal of Advanced Research and Reviews, 2023, 18(01), 554–557
Article DOI: 10.30574/wjarr.2023.18.1.0640
Publication history:
Received on 04 March 2023; revised on 13 April 2023; accepted on 15 April 2023
Abstract:
Multicentric Castleman's disease is a rare condition in HIV-infected patients that poses several difficulties in terms of diagnosis and treatment. The association of Multicentric Castleman's disease with the hemophagocytic syndrome is even less common and worsens the prognosis. Here we report a case of an HIV-infected patient with low-grade fever and pulmonary involvement with polyadenopathies diagnosed as multicentric Castleman's disease associated with the hemophagocytic syndrome, successfully treated with the combination of rituximab and etoposide.
Keywords:
HIV; Multicentric Castleman disease; HHV8; Hemophagocytic syndrome; Pulmonary involvement
Full text article in PDF:
Copyright information:
Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0