Discordance between fasting plasma glucose and A1c in the diagnosis and management of diabetes

Veerasak Sarinnapakorn, Chaicharn Deerochanawong *, Sathit Niramitmahapanya, Navaporn Napartivaumnuay and Thitinan Treesaranuwattana 

Endocrinology Unit, Department of Medicine, Rajavithi Hospital. College of Medicine, Rangsit University, Bangkok, Thailand.
 
Review Article
World Journal of Advanced Research and Reviews, 2021, 12(01), 243–255
Article DOI: 10.30574/wjarr.2021.12.1.0521
 
Publication history: 
Received on 07 September 2021; revised on 12 October 2021; accepted on 14 October 2021
 
Abstract: 
There are pros and cons of using fasting plasma glucose (FPG) and A1c for the diagnosis and management of diabetes. Still, discordance between FPG and A1c is a common problem in clinical practice, and there are no definite international guidelines for dealing with it. This article explains the causes of these anomalies and the factors that affect the results of tests, and it also recommends some appropriate techniques for investigation and management of cases of discordance between FPG and A1c.
 
Keywords: 
Fasting plasma glucose (FPG); A1c; Discordance; Diagnosis; Management
 
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